Introduction

Hey nude nutrition crew, today we are taking a look at an episode by Nathalie Niddam from the LONGEVITY podcast, featuring Boomer Anderson, the CEO of Smarter Not Harder and the maker of Transcriptions. This episode delves into the critical importance of sleep for longevity and immunity, and explores the science behind sleep supplements and their formulation.

• Guest and Main Theme: Boomer Anderson discusses sleep supplements, immunity, and longevity, highlighting the unique approach of Transcriptions.
• Expectations: Listeners can expect to learn about the link between sleep and immunity, how to evaluate supplement companies, and the innovative ingredients used in Transcriptions' products.

Evaluating Supplement Companies

Boomer Anderson emphasizes the importance of transparency and rigorous testing in the supplement industry.

• Transparency and Testing: Anderson advises consumers to ask for certificates of analysis, HPLC or NMR testing, and heavy metal and micro testing to ensure the purity and potency of supplements.
• Practitioner Involvement: He suggests working with a healthcare practitioner who can do the legwork to ensure the supplements are safe and effective.
• Clinical Effective Doses: Anderson stresses the importance of researching the clinically effective doses for ingredients to avoid ineffective or harmful products.
• Lab Tests: Using lab tests to analyze health markers can help filter out ineffective supplements and ensure the right dose is being taken.
• Regulatory Environment: The dietary supplement industry is lightly regulated, making it crucial for consumers to demand more from supplement companies.

Sleep and Immunity

The discussion focuses on the interconnection between sleep, immunity, and overall health.

• Sleep Architecture: Anderson explains the importance of maintaining proper sleep architecture, including deep sleep and REM sleep, for immune system repair and hormonal balance.
• Melatonin: Melatonin is discussed as a hormone that initiates sleep onset and has antioxidant properties, though it may have paradoxical effects on some individuals.
• Adenosine and GABA: The role of adenosine and GABA in inducing sleep is explored, with adenosine accumulating during the day to make one feel tired, and GABA acting as an inhibitory neurotransmitter.
• Corpin: Corpin, an extract from the Cordyceps mushroom, is highlighted for its role in deep sleep, immune system modulation, and anti-inflammatory properties.
• Sleep Disorders: Anderson touches on the consequences of sleep disorders, including cardiovascular disease, metabolic issues, and increased susceptibility to illnesses.

Transcriptions' Sleep Formula

The episode delves into the unique formulation of Transcriptions' sleep supplements.

• Buckle Troy Delivery Mechanism: The Buckle Troy lozenge delivery system is discussed, which bypasses first-pass metabolism and is close to the circulatory structure of the brain.
• Novel Ingredients: Anderson talks about the use of novel ingredients like appenine, melatonin, adenosine, and corpin, which are combined to address different aspects of sleep architecture.
• GABA Agonists and Positive Allosteric Modulators: The combination of GABA agonists and positive allosteric modulators, such as musal and hanuk kayal, is explained to enhance GABA production and release.
• CBD and CBN: The inclusion of CBD and CBN in the formula to improve GABA production through the endocannabinoid system is mentioned.
• Customizable Dosing: The scored trokies allow for customizable dosing to find the right dose for each individual.

Immune System Support with Corpin

Corpin's role in immune system support is detailed.

• Anti-inflammatory Properties: Corpin is discussed for its anti-inflammatory properties, inhibiting pro-inflammatory cytokines like TNF-alpha, IL-1b, and IL-6.
• Immune System Modulation: It is highlighted as an immune system modulator, helping with mast cell function and potentially useful for allergies.
• Antioxidant Properties: Corpin's antioxidant properties and its potential use in various health scenarios, including traumatic brain injury, are mentioned.
• Different Use Cases: The various ways people use corpin, such as for seasonal allergies, immune system regulation, and as an anti-inflammatory, are discussed.

Key Takeaways

• Importance of Sleep: Sleep is crucial for longevity and immunity, with proper sleep architecture being essential for health.
• Supplement Evaluation: Consumers should demand transparency and rigorous testing from supplement companies.
• Customized Formulations: Transcriptions' products are formulated with novel ingredients and customizable dosing to address individual needs.
• Interconnected Health: Sleep, immunity, and overall health are interconnected, and supporting one aspect can have broader health benefits.

Not-for-Profit Arm and Education

The episode concludes with a discussion on the not-for-profit arm of Transcriptions and its educational initiatives.

• Reciprocity Model: Boomer Anderson explains the reciprocity model between the for-profit and non-profit arms, focusing on educating healthcare practitioners.
• Health Optimization: The nonprofit, Home Hope, aims to teach nutrient and hormone balancing, clinical metabolomics, chronobiology, and other health optimization topics.
• Future Plans: The goal is to establish a specialty within the healthcare system that focuses on health rather than disease management, and to integrate AI in healthcare practices.